Defending champions Manchester United welcome Wigan Athletic, while Arsenal will travel to face either Norwich City or Southampton.
The winner of the replay between Plymouth or Liverpool will host Wolves. Chelsea host Brentford and Tottenham Hotspur are away to Wycombe.
FULL FA CUP 4TH ROUND DRAW
Tottenham vs Wycombe
Derby vs Leicester
Oxford vs Newcastle/Birmingham
AFC Wimbledon/Sutton United vs Cambridge/Leeds
Plymouth/Liverpool vs Wolves
Southampton/Norwich vs Arsenal
Lincoln/Ipswich vs Brighton
Chelsea vs Brentford
Manchester United vs Wigan
Millwall vs Watford
Rochdale vs Huddersfield
Burnley/Sunderland vs Fleetwood/Bristol City
Blackburn vs Barnsley/Blackpool
Fulham vs Hull
Middlesbrough vs Accrington Stanley
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